James M. Dieter III, NP-C, DC
Chairman of the Board and Chief Executive Officer, Principle Health Systems
James M. Dieter III is the visionary founder, Chairman, and CEO of Principle Health Systems (PHS), a dynamic, multi-vertical healthcare organization launched in 2015 to streamline and elevate patient care across diverse clinical settings. With over 20 years of hands-on experience in healthcare operations, clinical care, and business strategy, James leads PHS with a mission to build scalable, integrated service models that improve patient outcomes and experiences for patients and providers alike.
Under James’ leadership, PHS has grown into a comprehensive medical service ecosystem, encompassing a suite of mobile diagnostics including laboratory testing, imaging, and sonography. PHS delivers high-quality services to a broad network of specialty hospitals, skilled nursing facilities, and long-term care organizations—positioning itself as a trusted partner to physicians and practice groups across the United States.
James’ medical and operational expertise is rooted in a uniquely interdisciplinary background. His education includes specialization in Kinesiology – Applied Physiology, Biology, Nursing, and Chiropractic. He holds dual credentials as a Doctor of Chiropractic and a Board-Certified Family Nurse Practitioner (MSN), earned magna cum laude. He has completed extensive clinical work and residency rotations in orthopedics, pain management, internal medicine, pediatrics, and emergency care. His early-career clinical roles spanned inpatient hospital coverage, orthopedic surgery, interventional pain procedures, and neurological diagnostics.
James’ entrepreneurial journey began in 2009 with the construction and operation of an ambulatory surgical center. He later founded and scaled three healthcare businesses to profitability in under two years. He has continued to refine his approach through strategic acquisitions, centralized management infrastructure, and vertically integrated service delivery—earning PHS a reputation for rapid scalability, compliance-driven operations, and enhanced provider satisfaction.
Through ongoing organic growth and acquisitions, James and his team remain focused on expanding PHS’s reach while maintaining its commitment to personalized care and operational excellence. His deep-rooted connections to the Texas healthcare landscape, hands-on clinical expertise, and growth-oriented mindset make him a trusted partner for independent laboratories and diagnostic firms exploring strategic divestment opportunities.
A recognized leader in advanced diagnostics, James has presented research at the American Association for Clinical Chemistry and served as a subinvestigator in multiple Phase 3 clinical trials. His work in developing ancillary staffing models—such as cross-trained, full-time diagnostic technicians—paved the way for the formation of PHS, addressing widespread inefficiencies he encountered firsthand as a provider and entrepreneur.
James is a native Texan who has trained and worked in some of the state’s most respected institutions. Outside of his professional endeavors, he is an avid outdoorsman who enjoys skiing, fishing, hunting, and traveling with his family.
Education & Credentials
- MSN, Family Nurse Practitioner, Samford University (Magna Cum Laude)
- BSN, Hardin Simmons University (Cum Laude)
- DC & BS in Biology, Texas Chiropractic College
- BS in Kinesiology – Applied Physiology, Texas A&M University
- Board Certified Nurse Practitioner (NP-C), Licensed Chiropractor (DC)
- Certifications in Advanced Cardiac Life Support, Pain Management, Soft Tissue Rehabilitation, and Graston Technique
- Member, American Academy of Pain Medicine
Selected Affiliations & Accomplishments
- Founder and CEO, Principle Health Systems
- YPO, Young Presidents Organization
- Subinvestigator in FDA Phase 3 Clinical Trials
- Presenter, American Association for Clinical Chemistry
- Former Pain Committee Member, Clear Lake Regional Medical Center
- Cadaver Lab Instructor, Empire Medical Training
- Former Chief Intern, Moody Health Center
Core Competencies
- Strategic Acquisitions & Partnerships
- Value-Based Care Models
- Multi-site Healthcare Operations
- Clinical Workflow Optimization
- Ancillary Services & Diagnostic Integration
- Physician Alignment & Retention
- Regulatory Compliance & Risk Management
- Long-Term & Post-Acute Care Support
Notable Media & Publications:
- Principle Health Systems Acquires Telos PGX: A Strategic Move to Advance Personalized Healthcare
- Addison-Based BioStat Imaging Acquired by Houston’s Principle Health Systems
- Principle Health Systems Expands Reach with Acquisition of BioStat Laboratory in Dallas
- Shaping the Future of Healthcare with James M. Dieter III
- Trailblazing Healthcare Success with James Dieter
- Principle Health Systems Acquires Heartland Health Laboratory, Expanding Diagnostic Capabilities in the Midwest
Customer Testimonials

We transitioned to Principle Health for our Lab Provider, in my 30 + years I have never had such a smooth transition converting to a new lab, very impressed with the professionalism and communication! Thank you Team Principle!
Partnering with Principle Health Systems has been a game changer. Providing phlebotomy and PCR testing makes them a one stop shop for meeting patient needs. There are so many things that set this company apart. Communication, customer service, attention to detail and attitude of excellence, just to name a few. Highly recommend partnering with Prinicple Health Systems.
I would have to say that working with this company has been AMAZING! My rep is exceptionally FANTASTIC in coordinating you with the proper people to obtain any itemized billing and records needed, she has DEFINITELY made my job so much easier! Thank you!
Started a relationship with Principle last year with Touchstone Communities in our Houston area Communities. That was the start. This was followed with our new company, ML Healthcare. We wanted to continue this partnership with Principle in our new facility, Cypress Pointe Health and Wellness. Working with Principle has been great! They are true Partners in our healthcare facilities. Our organization values our relationship with Principle, and we look forward to continuing this relationship in our new facility – Sylvan Shores Health and Wellness.
Our Skilled Nursing Facility has used Principle Health Systems for the past three years. I have never reached out to them for assistance that I wasn’t able to connect with someone right away. They have skilled professional staff that provide excellent customer service and communication.
Fast and Friendly Service! Thank you Principle Health for keeping everyone safe during the testing process with your thorough cleanliness standards.
Principle has provided great services for our companies. We provide drug and alcohol treatment services, so timeliness with tox results is extremely important. We have always found Principle and their staff to be highly professional, responsive and efficient. We strongly recommend partnering with Principle and their team for your company’s service needs.
Great company to do business with. They have serviced my community and the residents and family were beyond pleased with their services!
This is a top-notch lab that goes above and beyond our needs at our clinics. They have met our every need and taken the time to educate the staff whenever the need arose.
Principle Health Systems is a very professional establishment that truly believes in customer service within and without of the organization. They are concerned about the needs of their patrons and believe in rectifying any matter with a positive lasting solution. They have amazing staff and awesome management which explains why they appear to be so successful.
Fast and Friendly Service! Thank you Principle Health for keeping everyone safe during the testing process with your thorough cleanliness standards.
Amazing company. The staff are complete pros and take care of their patients. Wouldn’t hesitate to recommend!